These transporter molecules also transport phenylalanine, tryptophan, methionine and department-chained amino acids. When tyrosine enters brain it should be transformed into DOPA (Dihydroxyphenylalanine) through tyrosine hydroxylase along with oxygen, iron and Tetrahydrobiopterin (THB) that act as co-factors. DOPA is transformed into dopamine through aromatic amino acid decarboxylase with pyridoxa L phosphate (PLP) co-thing. The price of reaction fluctuates while there's vitamin B deficiency. Central worried gadget has excessive share of dopaminergic cells than adrenergic cells.