many people, CBD oil has fewer side effects than prescription medications. Cannabidiol , has gained widespread attention for its potential to ease symptoms of insomnia, anxiety, chronic pain, and a host of other health conditions. Some recreational drugs, such as cannabis, will also increase tramadol side effects such as sleepiness and dizziness. If you take recreational drugs, such as cannabis, cocaine and heroin, while you are taking tramadol, you're more likely to get serious side effects.