Diverticular disease commonly occurs in people age above 40 years and the prevalence is increasing over the time. Approximately 10% of people over age 40 and 50% of people over age 60 encounter diverticular disease at some point in time. The disease was first identified in the 1930s, to share many of the hallmarks of inflammatory bowel disease. Diverticular disease is characterized by formation of small bulge or sacks called diverticula in the wall of colon. The sigmoid colon is more prone to formation of diverticula. These sacks may range from pea-size to much larger. The disease is associated with symptoms such as pain Men's Nike Air Max 95 Just Do It Shoes White Australia , bloating, nausea, diarrhea or constipation. Many of these symptoms are similar to inflammatory bowel disease. 20% of the patients may develop severe complications of diverticular disease such as abdominal or rectal bleeding. Diverticular disease are of three types聽viz. symptomatic uncomplicated diverticular disease, recurrent symptomatic diverticular disease and complicated diverticular disease. Standard treatment recommended for diverticular disease includes antibiotic therapies. Mesalazine (Asacol) and rifaximin (Xifaxan) are commonly recommended antibiotics for diverticular disease. Alternative therapies such as probiotics and diet modification may provide symptomatic relief and prevent recurrence Men's Nike Air Presto Fly Just Do It Shoes Black Australia , but are recommended along with standard antibiotics. There are two stages of diverticular disease聽viz. diverticulosis (presence of diverticula without complications) and diverticulitisan (inflammatory condition caused by perforation of the diverticula). Surgical treatment may be required in case of acute and recurrent diverticulitis.
Diverticular Disease Therapeutics Market: Drivers and Restraints
The growing prevalence and recurrence of diverticular disease is expected to be the major factor driving the growth of the diverticular disease therapeutics market over the forecast period. According to the World Journal of Gastrointestinal Pharmacology and Therapeutics, the prevalence of diverticular disease has increased from 35% to 50% in the last three decades. Changes is lifestyle and eating habits are attributed to growing prevalence of diverticular disease. Launch and addition of new therapies is the other factor contributing to the growth of the global diverticular disease therapeutics market. For instance, Cook Group Incorporated is evaluating Hemospray device in phase 2 clinical trial to control colonic bleeding in severe diverticular disease. Shire Plc. is evaluating SPD476 and SPD476 MMX in phase 3 clinical trial to reduce recurrence of diverticulitis.