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SAN FRANCISCO, March 14 (Xinhua) -- A professor with University of California, Berkeley Dre Kirkpatrick Bengals Jersey , is on a research team that paints lactate in a more sinister light -- as a key driver in the development and spread of cancer.
George Brooks, a renown researcher of the complex, often misunderstood molecule, spent two years working with Inigo San Millan, director of the sports performance department and physiology laboratory at the University of Colorado (CU) Sports Medicine and Performance Center at CU Boulder Vontaze Burfict Bengals Jersey , on a paper recently published in the journal Carcinogenesis.
For decades, lactate has been studied largely in the context of exercise, painted as a nagging metabolic byproduct that accumulates in the tissues and blood during workouts, stiffening muscles and hindering performance.
As far back as 1923, German Nobel laureate Otto Warburg observed that cancer cells take in exponentially more sugar Carlos Dunlap Bengals Jersey , or glucose, than normal cells. They inefficiently convert far less of it into energy, rather converting about 70 percent of it to lactate as a byproduct. The phenomenon, the first sign of a normal cell turning cancerous through abnormal cell metabolism, is known as the "Warburg effect."
With a heightened focus on genetics in recent decades Tyler Eifert Bengals Jersey , most researchers moved away from studying cancer metabolism, and the role of lactate became overshadowed, San Millan said.